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ECHA Calls for Information on Two Substances
ECHA would like to receive reproductive and sub-chronic toxicity data on 1,6-Bis((dibenzylthiocarbamoyl)disulfanyl)hexane and (1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate. More...
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ECHA Consults on Eleven Potential Substances of Very High Concern
The European Chemicals Agency (ECHA) has today published proposals to identify eleven chemicals as Substances of Very High Concern (SVHC) and possible candidates for authorisation. More...
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CERHR Calls for Information on Low-level Lead Exposure
CERHR invites the submission of information about ongoing studies or upcoming publications on the health effects of low-level lead exposure. This information will be considered in the CERHR’s evaluation of the potential health effects of exposure to low-level lead. More...
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EPA Announces Latest Chemical Action Plans
EPA to take action on benzidine dyes, hexabromocyclododecane (HBCD) and nonylphenol (NP)/nonylphenol ethoxylates (NPEs). The plans identify a range of actions the agency is considering under the Toxic Substances Control Act (TSCA). More...
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OSHA Seeks Input on Identifying the Top Chemicals of Concern
OSHA is hosting a Web forum asking for stakeholder input in identifying chemicals most in need of oversight to protect workers. The Forum will allow stakeholders to identify harmful chemicals and explain why OSHA should focus on these chemicals in developing long- and short-term solutions for reducing workers' exposure. More...
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EPA Releases Draft Document of Silver Nanomaterial Case Study
EPA is announcing a 45-day public comment period for the draft document, Nanomaterial Case Study: Nanoscale Silver in Disinfectant Spray (External Review Draft), as announced in the August 13, 2010 Federal Register Notice. The deadline for comments is September 27, 2010
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Notice of Intent to Establish a Maximum Allowable Dose Level (MADL) for Chromium (Hexavalent Compounds)
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) has proposed a MADL of 8.2 μg/day (oral) for chromium (hexavalent compounds). More...
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Notice of Intent to List S,S,S-tributyl phosphorotrithioate
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list S,S,S-tributyl phosphorotrithioate as known to the State to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986. This action is being taken under the authoritative bodies listing mechanism. More...
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Notice: IRIS Toxicological Review of Hexachloroethane (External Peer Review Meeting Announcement)
EPA announces an external peer review meeting for the review of the draft report, Toxicological Review of Hexachloroethane: In Support of Summary Information on the Integrated Risk Information System (IRIS) to be hosted on September 21, 2010 in Arlington, VA. More...
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California OEHHA Proposes Adding the Qualifying Term, “Oral” to the Maximum Allowable Dose Level (MADL) for Cadmium.
OEHHA is proposing to add the qualifying term, “(oral)” to the level to clarify that the adopted MADL of 4.1 micrograms per day for cadmium was and continues to be specific for the oral route of exposure. More...
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California OEHHA Publishes List of 27 Chemicals Identified for Consultation for Proposition 65 Listing
These chemicals will be discussed at the next meeting of the Proposition 65 Carcinogen Identification Committee (CIC) scheduled for Tuesday and Wednesday, September 21 and 22, 2010. More...
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Report on Carcinogens Moves Toward Completion
On June 21-22, 2010 NTP scientists presented draft substance reports for the final three compounds being considered for possible listing in the report for the Board of Scientific Counselors' consideration and public comment. More...
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ECHA Consults on Eight Draft Authorisation Recommendations
ECHA launches today a public consultation on its draft recommendation of eight substances to be included in the Authorisation List . These substances are: Diisobutyl phthalate (DIBP); Diarsenic trioxide; Diarsenic pentaoxide; Lead chromate; Lead sulfochromate yellow (C.I. Pigment Yellow 34); Lead chromate molybdate sulfate red (C.I. Pigment Red 104); Tris (2-chloroethyl) phosphate (TCEP); 2,4-Dinitrotoluene. Interested parties can submit comments until 30 September 2010. More...
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OEHHA Announces the Availability of Two Hazard Identification Documents
Documents entitled: "Evidence on the Carcinogenicity of 1,3-Dichloro-2-propanol (1,3 DCP)" and "Evidence on the Carcinogenicity of 3-Monochloropropane-1,2-diol (3-MCPD)" are now available. These two substances are being considered for possible listing under Proposition 65 by the CIC at its next meeting scheduled for Tuesday and Wednesday, September 21 and 22, 2010. More...
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Cal/EPA Extends Public Comment Period on TDI and MDI RELs
OEHHA has received a request from an interested party seeking an extension of the comment period to allow more time for the preparation of comments on the proposed MDI and TDI RELs. OEHHA has extended the public comment period for to 5 p.m., Thursday, July 22, 2010. More...
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Cal/EPA Withdraws Proposed No Significant Risk Level (NSRL) for Fumonisin B1
OEHHA is unable to complete the rulemaking process within the time allowed under the Administrative Procedure Act and is withdrawing its proposal to establish a specific level posing no significant risk using expedited methodology for Fumonisin B1. More...
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ECHA Member State Committee Supports Eight New Substances to Candidate List
The following substances may become subject to authorisation: Trichloroethylene ; Boric acid ; Disodium tetraborate anhydrous ; Tetraboron disodium heptaoxide hydrate ; Sodium chromate ; Potassium chromate ; Ammonium dichromate ; Potassium dichromate. More...
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Cal/EPA Revises Basis for Listing of Chlorsulfuron
Cal/EPA has changed the basis for listing Chlorsulfuron from "developmental, female, male" to only "developmental, female" based on new information from the U.S. EPA. More...
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California Proposes Revised RELs
The Office of Environmental Health Hazard Assessment (OEHHA) is soliciting public comments on a draft document describing proposed revised Reference Exposure Levels (RELs) for nickel and nickel compounds. More...
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EPA Releases the Toxicological Review of Formaldehyde-Inhalation Assessment
This draft IRIS health assessment addresses both noncancer and cancer human health effects that may result from chronic inhalation exposure to this chemical. More...
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ECHA Calls for Information to Avoid Unnecessary Animal Testing
ECHA would like to receive sub-chronic toxicity (90-day), reproductive toxicity (developmental toxicity), and reproductive toxicity (two-generation reproductive toxicity) for 2,3-epoxypropyl neodecanoate (CAS 26761-45-5) by July 12, 2010 in order to avoid duplicate animal testing. More...
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California Proposes REL for Caprolactam
The Office of Environmental Health Hazard Assessment (OEHHA) is releasing draft document describing proposed Reference Exposure Levels (RELs) for caprolactam to solicit public comment. More...
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California Adds N,N-Dimethylacetamide to Prop 65
The Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency is adding N,N-Dimethylacetamide (CAS No. 127-19-5) to the list of chemicals known to the state to cause reproductive toxicity. More...
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California Seeks Information on S,S,S-tributyl Phosphorotrithioate
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is requesting information as to whether S,S,S-tributyl phosphorotrithioate meets the criteria for listing under the Safe Drinking Water and Toxic Enforcement Act of 1986. More...
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EPA Announces the Release of the Final Report "An Exposure Assessment of Polybrominated Diphenyl Ethers"
This final report provides a comprehensive assessment of the exposure of Americans to this class of persistent organic pollutants. More...
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EPA Announces the Release of the Toxicological Review of Hexachloroethane
EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of hexachloroethane that will appear on the Integrated Risk Information System (IRIS) database. More...
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ECHA is Seeking Information on the Uses and Releases of Two Substances
The information on 2,4-dinitrotoluene and lead chromate is needed to help ECHA to judge whether they should be recommended as substances which should be subject to authorisation. More...
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ECHA Calls for Test Information
ECHA is seeking information on C8-C26 branched and linear hydrocarbons - Distillates to avoid unnecessary animal testing. More...
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EPA Announces the Availability of Literature Searches for Four IRIS Assessments
The EP A is also requesting scientific information on health effects that may result from exposure to these chemical substances: Diisobutyl Phthalate (DIBP), Diisononyl Phthalate (DINP), Dipentyl Phthalate (DPP), and Polychlorinated Biphenyls. More...
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Chemical Safety Board (CSB) Requests Public Comment on Methyl Isocyanate (MIC) Study
In a Federal Register notice published April 23, the CSB announced it is seeking public comment on the design of a Congressionally mandated study on the use of methyl isocyanate (MIC) in the manufacturing of certain pesticides, and the feasibility of implementing safer alternatives to protect workers and the public from a potential release. More...
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Cal/EPA Announces Proposed Revised Reference Exposure Levels for Toluene Diisocyanate and Methylene Diphenyl Diisocyanate
OEHHA has released draft documents describing proposed revised Reference Exposure Levels (RELs) for toluene diisocyanate and methylene diphenyl diisocyanate in order to solicit public comment. More...
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Cal/EPA Notice of Proposed Rulemaking - Di-isodecyl Phthalate (DIDP)
OEHHA proposes to establish a specific regulatory level having a maximum allowable dose (MADL) for Di-isodecyl Phthalate (DIDP). More...
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NTP Announces June Board of Scientific Counselors Meeting
Preliminary Agenda includes the peer review of 12th Report on Carcinogens (RoC) draft substance profiles and discussions of proposed CERHR research concepts and NTP Testing Program Nominations. More...
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EPA Announces Public Meetings on PCB Reassessment
EPA issued an Advance Notice of Proposed Rulemaking (ANPR) on the Agency's potential reassessment of its current authorizations for PCB use and distribution in commerce. The Agency will hold a series of public meetings around the country to provide stakeholders with the opportunity to provide comments, data and information on certain areas of the PCB regulations under the Toxic Substances Control Act (TSCA). More...
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EPA Proposes New Chemicals for the TRI List
The Agency announced that it is proposing to add 16 chemicals to the TRI list of reportable chemicals. The proposed chemicals
are ones that have been classified as “reasonably anticipated to be a human carcinogen” by the National Toxicology Program (NTP) in their Report on Carcinogens (RoC). More...
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Cal EPA Adds Three Chemicals to Prop 65
Bromochloroacetic acid (CAS No. 5589-96-8), Cumene (CAS No. 98-82-8) and Diclofop-methyl (CAS No. 51338-27-3) Listed as known to the state to cause Cancer. More...
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EPA Announces Call for Comments on Integrated Science Assessment (ISA) for Lead
This ISA is intended to update and revise the scientific assessment presented in the Air Quality Criteria for Lead published in October, 2006. More...
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ECHA Adds Acrylamide to SVHC Candidate List
The European Chemicals Agency has added Acrylamide (EC No 201-173-7 and CAS No 79-06-1)1 to the Candidate List of Substances Very High Concern (SVHC) for Authorisation. More...
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1,1-Dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and Nitrobenzene Added to Prop 65
The listings are effective March 30, 2010. More...
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OEHHA Announces Public Forum and Extension of Public Comment Period for Bispenol-A
OEHHA has scheduled a public forum on April 20th, 2010 and has extended the written public comment period to May 13, 2010. More...
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External Peer Review Comments available on the Toxicological Review of Ethyl Tertiary Butyl Ether (ETBE)
On January 26, 2010, an external peer review panel workshop was hosted by an independent contractor on the Toxicological Review of Ethyl Tertiary Butyl Ether (External Review Draft). Completing this review, a final report of the comments from the workshop were collected and is now available on the EPA website. More...
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NTP Board of Scientific Counselors (BSC) Announces Meeting and Request for Comments
The preliminary agenda topics are the agency's recent activities on Soy Infant Formula and low-level Lead. More...
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Draft Technical Support Document for the Proposed Public Health Goal (PHG) for Styrene now Available
The OEHHA announces a 60-day extension of the public comment period on the draft technical support document for the proposed Public Health Goal (PHG) for styrene in drinking water. More...
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OEHHA Extends Public Comment Period for Epoxiconazole
On February 5, 2010, OEHHA published a notice soliciting information relevant to the evaluation of epoxiconazole. OEHHA subsequently received a request from an interested party seeking an extension of the comment period and has consequently extended the public comment period until April 7, 2010. More...
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OEHHA to Establish Specific Regulatory Levels for Acrylamide
The proposed regulation would adopt a MADL of 140 micrograms per day, which is 700 times greated than the current NSRL of 0.2 micrograms per day. More...
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OEHHA to List Acrylamide as a Reproductive Toxicant
This action is being taken under the authoritative bodies listing mechanism. Acrylamide meets the criteria for listing as known to the State to cause reproductive toxicity under Proposition 65, based on findings of NIOSH and NTP-CERHR. More...
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OEHHA to Add Metam Potassium to Prop 65
OEHHA has determined that Metam potassium meets the regulatory criteria for listing as known to the State to cause cancer based on the findings of the U.S. EPA (U.S. EPA, 1995; 2005; 2007; 2009). More...
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ECHA Announces Public CLP Consultation on 4 Substances
The public consultation on harmonised classification and labelling for acequinocyl, metazachlor, tris(nonylphenyl) phosphate and bifenthrin begins on 2/22/2010. More...
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EPA Announces the Release of the Toxicological Review of Inorganic Arsenic (External Review Draft)
This draft assessment is provided for a 60-day public viewing and comment period. More...
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OEHHA proposes NSRLs for p-Chloroaniline and p-Chloroaniline Hydrochloride
The “No Significant Risk Level” (NSRL) is defined in regulation as the daily intake level posing a 10-5 lifetime risk of cancer. The NSRLs for p-chloroaniline hydrochloride and p-chloroaniline are calculated to be 1.9 μg/day and 1.5 μg/day, respectively. More...
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EPA announces the release of the National Research Council's Review of the Draft IRIS Assessment of Tetrachloroethylene
The NRC report concludes that the EPA's classification of tetrachloroethylene as "likely to be a human carcinogen" is appropriately supported. More...
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OEHHA Requests Information on Bisphenol A
OEHHA is requesting public comment concerning whether this chemical meets the criteria for listing as known to the State to cause reproductive toxicity under Proposition 65. More...
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OEHHA Notice of Intent to List Diclofop-Methyl and Epoxiconazole
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list the chemicals diclofop-methyl and epoxiconazole as known to the State to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986. More...
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OEHHA Notice of Intent to List Bromochloroacetic Acid and Cumene
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list the chemicals bromochloroacetic acid and cumene as known to the State to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986. More...
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OEHHA Adds Carbaryl to Prop 65
Carbaryl (CAS No.63-25-2) is being listed as a chemical known to the State of California to cause cancer. The listing of this chemical is based on formal identification by an authoritative body (the U.S. Environmental Protection Agency (U.S. EPA)), that the chemical causes cancer. More...
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Comments available on the Toxicological Review of Chloroprene
On January 6, 2010, an external peer review panel workshop was hosted by an independent contractor on the Toxicological Review of Chloroprene (External Review Draft). Completing this review, a final report of the comments from the workshop were collected and is now available. More...
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Notice: Exposure Factors Handbook 2009 Update (External Review Draft) External Peer Review Meeting Announcement
EPA announces the details of an external peer review meeting to be held on March 3-4, 2010. This draft document, Exposure Factors Handbook 2009 Update (External Review Draft) was previously provided for public viewing and comment. More...
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State of Washington Releases Draft List of Chemicals on the Children’s Product Safety Act
List of 66 chemicals is part of the pilot rule-making process related to the previously enacted Children’s Product Safety Act. More...
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OEHHA Notice of Intent to List DDE and Nitrobenzene
The California Environmental Protection Agency's Office of Environmental Health Hazard Assessment (OEHHA) intends to list the chemicals 1-dichloro-2,2-bis(p-chlorophenyl) ethylene (DDE) and nitrobenzene as known to the State to cause reproductive toxicity under the Safe Drinking Water and Toxic Enforcement Act of 1986. More...
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EPA Releases Final Report on Carbon Monoxide
EPA is announcing the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) Final Report. This is EPA’s latest evaluation of the scientific literature on the potential human health and welfare effects associated with ambient exposures to CO. The development of this document is part of the Agency's periodic review of the national ambient air quality standards (NAAQS) and will provide the scientific basis to inform EPA decisions related to the review of the current CO standards. More...
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Comments available on the Toxicological Review of cis- and trans-1,2-dichloroethylene
On December 17, 2009, an external peer review panel workshop was hosted by an independent contractor on the Toxicological Review of Cis-and Trans-1,2-Dichloroethylene (External Review Draft). Completing this review, a final report of the comments from the workshop were collected and is now available. More...
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Comments Available on the Toxicological Review of Hydrogen Cyanide and Cyanide Salts
On December 14, 2009, an external peer review panel workshop was hosted by an independent contractor on the Toxicological Review of Hydrogen Cyanide and Cyanide Salts (External Review Draft). Completing this review, a final report of the comments from the workshop were collected and is now available. More...
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Comments Available on the EPA Toxicological Review of Trichloroacetic Acid
On December 10, 2009, an external peer review panel workshop was hosted by an independent contractor on the Toxicological Review of Trichloroacetic Acid (External Review Draft). Completing this review, a final report of the comments from the workshop were collected and is now available. More...
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European Chemicals Agency Publishes Public CLP Consultations on Three Chemical Substances.
ECHA seeking comment on White Spirits, Fuberidazole, and Thiacloprid. More...
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FDA Update on Bisphenol A (BPA) for Use in Food
FDA has released a 2010 update on the status of its activities to answer key questions and clarify uncertainties about the risks of BPA. More...
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EPA Announces the Release of the Draft IRIS Toxicological Review of Methanol
A listening session will be held on February 23, 2010, during the public comment period for this draft document. More...
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CERHR Announces the Availability of the Final Expert Panel Report on Soy Infant Formula
CERHR invites written public comments by March 1, 2010. More...
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WHO Planning Expert Consultation on Bisphenol A
The World Health Organization's department of Food Safety and Zoonoses has released a call for data and call for experts to consult on their planned assessment of the toxicological and health effects of bisphenol A. More...
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REACH Candidate List of Substances of Very High Concern for Authorisation Grows
The European Chemicals Agency has added 14 chemical substances to the Candidate List of Substances of Very High Concern (SVHC) for authorisation. Companies manufacturing or importing these substances need to check their potential obligations that result from the listing. More...
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OEHHA Extends Public Comment Period for Spirodiclofen
OEHHA has received a request from an interested party seeking an extension of the comment period to allow for the submission of complete and relevant scientific information for spirodiclofen. OEHHA hereby extends the public comment period two weeks to 5 p.m., Monday, January 25, 2010. More...
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Clodinafop-Propargyl and Metofluthrin Not Listed Under Prop 65
In view of this change in the cancer classifications of the chemicals by the U.S. EPA, OEHHA will not proceed with the proposed listing of these chemicals as known to cause cancer via the authoritative bodies mechanism at this time. More...
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IRIS Toxicological Review of Ethyl Tertiary Butyl Ether: Notice of Peer-Review Workshop
EPA announces the details of an external peer-review workshop to be held on January 26, 2006. This draft assessment, Toxicological Review of Ethyl Tertiary Butyl Ether: In Support of Summary Information on the Integrated Risk Information System (IRIS) was previously provided for public viewing and comment. More...
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IRIS Toxicological Review of Trichloroethylene: Public Listening Session Announcement
EPA is announcing a listening session to be held on January 26, 2006, during the public comment period for the draft document entitled, Toxicological Review of Trichloroethylene: In Support of Summary Information on the Integrated Risk Information System (IRIS). More...
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NTP Publishes Actions from the NTP Board of Scientific Counselors Technical Reports Review Subcommittee Meetings
Results of the November 19, 2009 Meeting now available on the NTP website. More...
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RoC Requests Public Comments on Formaldehyde
The NTP invites public comment on the recommendation from an expert panel on the listing status for formaldehyde in the 12th RoC and the scientific justification for the recommendation. More...
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Cal EPA Adds Four Chemicals to Prop 65
Wood dust and zidovudine (AZT) are being added to the list as known to the state to cause cancer. Tert-Amyl methyl ether (TAME) and ethyl-tert-butyl ether (EBTE) are being added as known to the state to cause reproductive toxicity. These listings are effective December 18, 2009. More...
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Notice of IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane: External Peer-Review Workshop
EPA will will convene an independent panel of experts and organize and conduct an external peer-review workshop to review the external review draft document titled, "Toxicological Review of 1,1,2,2-Tetrachloroethane: In Support of Summary Information in the Integrated Risk Information System (IRIS)" More...
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CDC Releases National Report on Human Exposure to Environmental Chemicals
The Fourth National Report on Human Exposure to Environmental Chemicals is the most comprehensive assessment to date of the exposure of the U.S. population to chemicals in our environment. More...
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Molinate Added to Cal Prop 65
The Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency is adding molinate (CAS No. 2212-67-1) to the list of chemicals known to the state to cause reproductive toxicity for purposes of Proposition 65. The listing of molinate is effective December 11, 2009. More...
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OEHHA Extends Comment Period on Three Chemicals
OEHHA has received requests to extend the comment period for (1,3-DCP), 3’monochloropropane-1,2-diol (3-MCPD), and perfluorooctanoic acid (PFOA) and its salts and transformation and degradation precursors to allow for the submittal of complete and relevant scientific information. More...
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15 New Substances of Very High Concern (SVHC) to be Added to the Candidate List
ECHA´s Member State Committee identified today 15 new chemical substances for the Candidate List of substances of very high concern. The List will formally be updated in January 2010. More...
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NTP Expert Panel Recommends Listing Formaldehyde as Known Human Carcinogen
On November 4, a 10-member independent scientific expert panel convened by the National Toxicology Program (NTP) voted unanimously to list formaldehyde as a "known human carcinogen" in the upcoming 12th NTP Report on Carcinogens (RoC). More...
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ECHA Calls Again for Information to Avoid Unnecessary Animal Testing
The European Chemicals Agency (ECHA) is calling for information on the long-term health effects of “4-((Triethoxysilyl)methyl)morpholine”. This is a public consultation foreseen by the REACH Regulation for testing proposals involving animals. More...
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Notice of IRIS Toxicological Review of Chloroprene: External Peer-Review Workshop
EPA will will convene an independent panel of experts and organize and conduct an external peer-review workshop to review the external review draft document titled, "Toxicological Review of Chloroprene: In Support of Summary Information in the Integrated Risk Information System (IRIS)" More...
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Cal EPA Announces Intent to List Two Chemicals on Prop 65
OEHHA has determined that Carbaryl and Spirodiclofen meet the regulatory criteria for listing based on the findings of the U.S. EPA. More...
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ECHA Calls for Information to Avoid Unnecessary Animal Testing
The European Chemicals Agency (ECHA) is calling for information on the health effects of a new substance with the name of “Polysulfo{5-hydroxy-1-naphthalen-2-yl-[4-[4-(2-sulfatoethyl-sulfonyl)-phenyl]diazenyl]-1H-pyrazole-3-carboxylic acid}, alkali metal salt”. This is a public consultation foreseen by the REACH Regulation for testing proposals involving animals. More...
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Request for Relevant Information on Chemicals Being Considered for Listing by the Authoritative Bodies Mechanism: Clodinafop-Propargyl, Diclofop-Methyl, and Epoxiconazole
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is requesting information as to whether three chemicals meet the criteria for listing under the Safe Drinking Water and Toxic Enforcement Act of 1986. This action is being proposed under the authoritative bodies listing mechanism. More...
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EU Council Paves Way to New IOELVs List
The Council decided not to oppose a Commission decision to establish a further list of indicative occupational exposure limit values (IOELVs) for the protection of workers from chemical risks. More...
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EPA Announces the Release of the Draft Toxicological Review of Trichloroethylene
This draft assessment is provided for public review and comment. Public comments received on the Toxicological Review within 90 days after the release of the FRN (on or before February 1, 2010) will be provided to the external peer reviewers for their consideration. More...
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OEHHA Requests Comments on Potential Reproductive and Developmental Toxicants
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is requesting information as to whether 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and nitrobenzene meet the criteria for listing as reproductive toxicants under the Safe Drinking Water and Toxic Enforcement Act of 1986. More...
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EPA Orders Chemical Testing for Hormone Effects
The U.S. Environmental Protection Agency has issued the first test orders for pesticide chemicals to be screened for their potential effects on the endocrine system. Endocrine disruptors are chemicals that interact with and disrupt the hormones produced or secreted by human and animal endocrine systems, which regulate growth, metabolism and reproduction. More...
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ATSDR Announces Final Priority Data Needs for Six Priority Hazardous Substances
This notice announces the final priority data needs for six priority hazardous substances as part of the continuing development and implementation of the ATSDR Substance Specific Applied Research Program (SSARP). This notice also serves as a continuous call for voluntary research proposals. More...
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NTP Board of Scientific Counselors (BSC) Announces Meeting and Request for Comments
The preliminary agenda, roster of BSC members and ad hoc reviewers, background materials for agenda topics, public comments, and any additional information, when available, will be posted on the BSC meeting Web site. More...
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EPA Releases Round 2 Comments on EPA’s Revised Draft Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE)
On April 25, 2008, the Toxicological Review of ethylene glycol monobutyl ether (EGBE) was released for external review. Comments from the first and second rounds of this review were consolidated and reports are now available. More...
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EPA Releases Final Peer Review Summary Report on the EPA/IRIS Draft Toxicological Review of Pentachlorophenol
On August 4, 2009, an external peer review panel workshop was hosted by an independent contractor on the Toxicological Review of Pentachlorophenol (External Review Draft). Completing this review, a final report of the comments from the workshop were collected and is now available. More...
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EPA Announces 2009/2010 IRIS Update Project Agenda
The intent of the IRIS Update Project is to revisit all dose-response assessment toxicity values such as oral reference doses (RfDs), inhalation reference concentrations (RfCs), cancer oral slope factors, and cancer inhalation unit risks in IRIS with a posting or entry date of more than 10 years old. More...
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OEHHA Receives Request to Delist Chlorsulfuron
OEHHA's response to the DuPont request is pending. More...
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The CERHR Announces Availability of the Draft Expert Panel Report on Soy Formula, Request for Public Comment and Expert Panel Meeting
The Center for the Evaluation of Risks to Human Reproduction (CERHR) invites public comments on the draft expert panel report which is an update to a previous expert panel evaluation completed in 2006. The expert panel will meet in December to review and revise the draft expert panel report and reach conclusions regarding whether exposure to soy formula is a hazard to human development. More...
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ChemSec Updates SIN List
The SIN List 1.0 has been updated with 89 new substances. This update of the SIN List is due to an extension of the list of substances classified within the European Union as CMRs– Carcinogenic, Mutagenic, and toxic to Reproduction. Based as always on the REACH criteria for Substances of Very High Concern, the SIN List now contains 356 substances to be Substituted Now! More...
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Cal EPA Requests Relevant Information on Chemicals Being Considered for Listing by the Authoritative Bodies Mechanism
The Office of Environmental Health Hazard Assessment (OEHHA) is requesting information as to whether bromochloroacetic acid and cumene meet the criteria for listing under the Safe Drinking Water and Toxic Enforcement Act of 1986. This action is being proposed under the authoritative bodies listing mechanism. More...
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Cal EPA Announces Five Chemicals for Possible Listing on Prop 65
The Office of Environmental Health Hazard Assessment (OEHHA) has initially selected five chemicals for the CIC’s review for possible listing under Proposition 65 and is initiating the development of hazard identification materials for these chemicals. Under consideration are: 3-Monochloropropane-1,2-diol; 1,3-Dichloro-2-propanol; Fluoride and its salts; Diisononyl phthalate (DINP); Perfluorooctanoic acid (PFOA) and its salts and transformation and degradation precursors. More...
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EPA Releases Final Drinking Water Contaminant Candidate List 3
The CCL 3 is a list of contaminants that are currently not subject to any proposed or promulgated national primary drinking water regulations, that are known or anticipated to occur in public water systems, and which may require regulation under SDWA. More...
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OEHHA Proposes NSRL for Fumonisin B1
This amendment to Section 25705(d) would adopt 1.5 micrograms/day as the No Significant Risk Level (NSRL). More...
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ECHA Publishes List of REACH Registered Substances
The list is based on the complete registration dossiers submitted by companies to ECHA before 24 September 2009 and contains 156 substances. More...
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EPA Begins New Scientific Evaluation of Atrazine
The U.S. Environmental Protection Agency is launching this year a comprehensive new evaluation of the pesticide atrazine to determine its effects on humans. At the end of this process, the agency will decide whether to revise its current risk assessment of the pesticide and whether new restrictions are necessary to better protect public health. More...
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Notice for the Toxicological Review of Chloroprene: External Peer Review Draft
EPA is announcing a public comment period for the external review draft document titled, ``Toxicological Review of Chloroprene: In Support of Summary Information on the Integrated Risk Information System (IRIS)''. More...
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EPA Releases Tox Profile on 2-Hexanone and Publishes New IRIS Summary
Comments received during the interagency science discussion on 2-hexanone will be posted with the external review draft within the next few weeks. More...
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Notice for the Toxicological Review of Trichloroacetic Acid: External Peer Review Draft & Listening Session
EPA is announcing a public comment period to review the draft document titled, "Toxicological Review of Trichloroacetic Acid: In Support of Summary Information on the Integrated Risk Information System (IRIS) (External Review Draft)." EPA is also announcing a public listening session to be held on November 4, 2009. Comments received during the interagency science discussion on Trichloroacetic Acid will be posted with the external review draft within the next few weeks. More...
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Notice for the Toxicological Review of Cis-and Trans-1,2-Dichloroethylene: External Peer Review Draft & Listening Session
EPA is announcing a public comment period to review the draft document titled, "Toxicological Review of Cis-and Trans-1,2-Dichloroethylene: In Support of Summary Information on the Integrated Risk Information System (IRIS) (External Review Draft)." EPA is also announcing a public listening session to be held on October 19, 2009. Comments received during the interagency science discussion on Cis- and Trans-1,2-Dichloroethylene will be posted with the external review draft within the next few weeks. More...
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Notice for the Toxicological Review of 1,1,2,2-Tetrachloroethane: External Peer Review Draft & Listening Session
EPA is announcing a public comment period to review the draft document titled, "Toxicological Review of 1,1,2,2-Tetrachloroethane: In Support of Summary Information on the Integrated Risk Information System (IRIS) (External Review Draft)." EPA is also announcing a public listening session to be held on October 14, 2009. More...
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EPA Releases External Draft of the Toxicological Review of Ethyl Tertiary Butyl Ether
EPA is announcing a listening session to be held on October 7, 2009, for the external review draft document entitled, "Toxicological Review of Ethyl Tertiary Butyl Ether: In Support of Summary Information on the Integrated Risk Information System (IRIS)." More...
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EPA Releases Draft Document of the Integrated Science Assessment for Carbon Monoxide
This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA's decision regarding whether the current standards for CO sufficiently protect public health and the environment. More...
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EPA Releases External Draft of the Toxicological Review of Hydrogen Cyanide and Cyanide Salts
EPA's IRIS Program is announcing a public comment period to review the draft document titled, "Toxicological Review of Hydrogen Cyanide and Cyanide Salts (External Review Draft)." EPA is also announcing a public listening session to be held on October 27, 2009. More...
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EPA Releases Tox Profile on Chlordecone (Kepone) and Publishes New IRIS Summary
Comments received during the interagency science discussion on chlordecone will be posted with the external review draft within the next few weeks More...
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Canada Amends DSL to Apply SNAc Provision to Disperse Orange 5
On September 16, 2009 an Order amending the Domestic Substances List (DSL) to apply the Significant New Activity (SNAc) provisions specified under subsection 81(3) of CEPA 1999 for Disperse Orange 5 (CAS No. 6232-56-0), substance in Batch 5 of the Challenge, was published in the Canada Gazette, Part II. More...
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OEHHA Extends Public Comment Period on Proposed Public Health Goal for Antimony
The Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency is hereby announcing a 30-day extension of the public comment period on the draft technical support document for the proposed Public Health Goal (PHG) for antimony in drinking water. More...
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New Public Consultation on Harmonised Classification and Labelling of Three Chemical Substances
ECHA publishes public consultation on the proposal to harmonize the classification and labelling of three chemical substances. Comments are welcome on the proposal within the next 45 days. More...
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New Public Consultation on 15 Potential Substances of Very High Concern (SVHC)
The European Chemicals Agency (ECHA) has published proposals to identify chemicals as Substances of Very High Concern (SVHC). Interested parties are welcome to comment on these 15 substances within the next 45 days. More...
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NTP Announces the Availability of the Draft Background Document for Formaldehyde
The NTP invites the submission of public comments on the draft background document for formaldehyde. The expert panel will meet on November 2–4, 2009 to peer review the draft background document for formaldehyde and, once completed, make a recommendation regarding the listing status in the 12th Edition of the RoC (12th RoC). More...
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OEHHA Publishes Final Technical Support Document for the Public Health Goal (PHG) for the Solvent 1,2,3-trichloropropane in Drinking Water
This document establishes a PHG for 1,2,3-trichloropropane of 0.0007 parts per billion, versus the current Notification Level of 0.005 ppb, set in 2005. The PHG is based on an updated cancer potency calculation. More...
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Canada Amends the DSL to Apply the SNAc Provisions to Six Pesticides
On August 19th, 2009, an Order amending DSL to apply the Significant New Activity (SNAc) provisions specified under subsection 81(3) of CEPA 1999 to 6 substances was published in the Canada Gazette, Part II. More...
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EPA Releases Draft Toxicological Review of Ethyl Tertiary Butyl Ether
The draft Toxicological Review of Ethyl Tertiary Butyl Ether provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to ethyl tertiary butyl ether. Public comments received within 60 days will be provided to the external peer reviewers for their consideration. More...
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Canada Amends the DSL to Apply the SNAc Provisions to Fluorotriphenyltin and Tetraphenyltin
On August 19th, 2009, an Order amending the Domestic Substances List (DSL) to apply Significant New Activity (SNAc) provisions specified under subsection 81(3) of CEPA 1999 to Fluorotriphenyltin and tetraphenyltin, was published in the Canada Gazette, Part II. More...
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Canada Amends the DSL to Apply the SNAc Provisions to five Batch 4 substances
On August 19, 2009 an Order amending the Domestic Substances List (DSL) to apply the Significant New Activity (SNAc) provisions specified under subsection 81(3) of CEPA 1999 to five of the substances in Batch 4 (CAS No. 1154-59-2, 1176-74-5, 64325-78-6, 68443-10-7 and 70776-86-2), was published in the Canada Gazette, Part II. More...
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New NCEA Policy and Procedures for Conducting IRIS Peer Reviews
EPA releases an updated policy and procedure guidance for conducting IRIS Peer Reviews which discusses the issue of conflict of interest and and appearance of bias or lack of impartiality when a peer review panel is being formed. More...
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